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Regulation of Na+ pump function by aldosterone is alpha-subunit isoform specific

R Pfeiffer1, J Beron, F Verrey

  • 1Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

The Journal of Physiology
|April 14, 1999
PubMed
Summary

Aldosterone rapidly activates sodium pumps (Na+,K+-ATPase) in kidney cells. This early activation specifically targets pumps with the alpha1 subunit, not alpha2 or alpha3, revealing a key regulatory mechanism.

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