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Related Experiment Videos

Abnormalities of the electrogastrogram in functional gastrointestinal disorders.

A Leahy1, K Besherdas, C Clayman

  • 1Department of Gastroenterology, Royal Free Hospital, London, United Kingdom.

The American Journal of Gastroenterology
|April 14, 1999
PubMed
Summary
This summary is machine-generated.

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Electrogastrography (EGG) is abnormal in 36% of functional dyspepsia patients, showing 93% specificity. EGG abnormalities in irritable bowel syndrome patients are linked to concurrent dyspepsia symptoms.

Area of Science:

  • Gastroenterology
  • Medical Diagnostics
  • Physiology

Background:

  • Cutaneous electrogastrography (EGG) records gastric electrical activity and detects arrhythmias.
  • Abnormalities in EGG are noted in various disorders, but their specificity and prevalence in functional gastrointestinal disorders remain unclear.

Purpose of the Study:

  • To assess the specificity of EGG.
  • To determine the prevalence and pattern of EGG abnormalities in functional dyspepsia (FD) and irritable bowel syndrome (IBS).

Main Methods:

  • EGG was performed on 170 FD patients, 70 IBS patients, 20 GERD patients, and 30 controls.
  • An abnormal EGG was defined as <70% normal electrical activity before or after a test meal.

Main Results:

Related Experiment Videos

  • EGG was abnormal in 36% of FD patients and 25% of IBS patients with dyspepsia.
  • EGG was normal in 93% of controls, 90% of GERD patients, and 92% of IBS patients without dyspepsia.
  • FD patients showed significantly more tachygastrias and unstable electrical frequency post-meal.

Conclusions:

  • EGG is abnormal in ~36% of FD patients with approximately 93% specificity.
  • EGG identifies a subgroup of FD patients with gastric electrical rhythm disturbances.
  • In IBS, EGG abnormalities typically occur only when dyspepsia is also present.