Borderline personality disorder and bone marrow transplantation: ethical considerations and review
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Updated: Oct 23, 2026

Bone Marrow Transplantation Platform to Investigate the Role of Dendritic Cells in Graft-versus-Host Disease
Published on: March 17, 2020
M A Weitzner1, F Lehninger, D Sullivan
1Psychosocial Oncology Program, H. Lee Moffitt Cancer Center, Tampa, Florida 33612-9497, USA. weitznma@moffitt.usf.edu
Abstract:
Bone marrow transplantation (BMT) is rapidly becoming a part of conventional cancer treatment. However, it remains a 'last-ditch' treatment option for patients who have exhausted other treatment modalities. Patients experience a significant amount of emotional distress during all stages of the BMT process. Patients with personality disorders experience even more emotional distress than average and their behavior is often detrimental to effective patient-staff interactions. A case of a borderline patient is presented with a discussion of the ethical issues involved in the evaluation of these patients and the determination of their appropriateness for transplant.
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