[Influence of personality disorder on the course of manic-depressive illness]

In these past years, comorbidity of manic-depressive illness with personality disorders were the subject of many studies. In order to study the influence of personality disorder on the course of the disease, the authors have compared a group of manic depressive patients with personality disorders to an other group of manic depressive patients without personality disorders. The comparison between the outcome and prognosis of each group has leaded to the conclusion that manic depressive patients with personality disorders evaluate worse than those without personality disorders: they are more often hospitalized and have more suicide attempts, they are more vulnerable to stress factors and finally they have low scores on the Global Assessment of Functioning scale (GAF).