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Published on: December 24, 2013
Serotonin transporter gene (5-HTT) polymorphisms and compulsive buying
E J Devor1, H J Magee, R M Dill-Devor
1Integrated DNA Technologies, Coralville, Iowa 52241, USA. rdevor@idtdna.com
Abstract:
We examined a panel of 21 patients diagnosed with compulsive buying for two DNA sequence polymorphisms found in the gene that encodes the serotonin transport (5-HTT). One polymorphism, found in the promoter region of the 5-HTT gene, involves a 44-base pair (bp) deletion, and the other, found in the second intron, is due to variable numbers of a repeat sequence. We also typed a panel of 38 psychiatrically normal controls for both 5-HH markers. When compared to this control panel, no significant differences were seen for either 5-HTT marker among the compulsive buyers.
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