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Updated: Aug 14, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
06:35

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Published on: June 28, 2021

Platelet-activating factor and platelet-activating factor antagonists in acute pancreatitis

C D Johnson1

  • 1University Surgical Unit, Southampton General Hospital, Southampton, UK. c.d.johnson@soton.ac.uk

Digestive Surgery
|April 20, 1999
PubMed
Summary

Platelet-activating factor (PAF) exacerbates acute pancreatitis, leading to organ failure. PAF antagonists, like lexipafant, show promise in reducing inflammation and improving outcomes in severe cases.

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