Related Experiment Video
Updated: Aug 12, 2026
Acquiring Hyperpolarized 129Xe Magnetic Resonance Images of Lung Ventilation
Published on: November 21, 2023
Lung air spaces: MR imaging evaluation with hyperpolarized 3He gas
E E de Lange1, J P Mugler, J R Brookeman
1Department of Radiology, University of Virginia Health Sciences Center, Charlottesville 22908, USA.
Abstract:
Thirty-two magnetic resonance imaging examinations of the lungs were performed in 16 subjects after inhalation of 1-2 L of helium 3 gas that was laser polarized to 10%-25%. The distribution of the gas was generally uniform, with visualization of the fissures in most cases. Ventilation defects were demonstrated in smokers and in a subject with allergies. The technique has potential for evaluating small airways disease.
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