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[Interactions between naltrexone, an opioid antagonist, and opioids administered during general anesthesia]
B Tesson1, A Bigot-Viale, J P Vigue
1Département d'anesthésie-réanimation chirurgicale, CHRU, Angers, France.
Annales Francaises D'Anesthesie Et De Reanimation
|April 20, 1999
Abstract:
We report a case of a probable interaction between sufentanil and naltrexone, an oral long acting opioid antagonist, prescribed for maintenance of abstinence in alcoholics and opioid addicts. The interaction resulted in an antagonisation of the effects of sufentanil and the necessity to increase the dosage. Anaesthetists should be aware of this potential drug interaction.