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Subclinical hyperthyroidism and hyperkinetic behavior in children.

P A Suresh1, S Sebastian, A George

  • 1Section of Speech and Behavioural Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.

Pediatric Neurology
|April 20, 1999
PubMed
Summary
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Subclinical hyperthyroidism in children can manifest as developmental learning disabilities (DLDs) and behavioral issues. Early thyroid screening in at-risk children may improve attention and learning outcomes.

Area of Science:

  • Pediatric Endocrinology
  • Developmental Neuroscience
  • Behavioral Pediatrics

Background:

  • Developmental learning disabilities (DLDs) are frequently associated with behavioral disturbances, including attention deficit and hyperactivity.
  • Routine endocrinologic evaluations are often performed for children with DLDs.

Observation:

  • Three children with DLDs presented with behavioral issues like attention deficit, hyperactivity, and autistic features.
  • Thyroid function tests revealed subclinical hyperthyroidism in these children, despite the absence of overt systemic symptoms.

Findings:

  • Treatment with neomercazole effectively managed hyperkinetic behavior and improved language function.
  • Improvements were linked to enhanced attention spans, which facilitated speech therapy.

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Implications:

  • Selective thyroid screening in children with a family history of attention-deficit hyperactivity disorder (ADHD) or those with ADHD and DLDs is warranted.
  • This approach may lead to earlier diagnosis and intervention for related behavioral and learning challenges.