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Poliomyelitis-like syndrome associated with Epstein-Barr virus infection
M Wong1, A M Connolly, M J Noetzel
1Department of Neurology, Washington University School of Medicine, St. Louis Children's Hospital, Missouri.
Pediatric Neurology
|April 20, 1999
Abstract:
A 20-month-old male presented with an acute clinical syndrome resembling poliomyelitis, characterized by a flaccid monoplegia, areflexia of the involved limb, and preserved sensation. Electrophysiologic studies supported a neuronopathic localization involving the anterior horn cells. Although laboratory evidence for a poliovirus infection was absent, serologic and polymerase chain reaction studies documented an active central nervous system infection with Epstein-Barr virus, indicating that a poliomyelitis-like syndrome may be produced by infectious agents other than enteroviruses.