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Updated: Aug 30, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
Published on: January 13, 2017
Plant natural products: the molecular genetic basis of biosynthetic diversity
1Plant Biology Division, The Samuel Roberts Noble Foundation, 2510 Sam Noble Parkway, Ardmore, Oklahoma 73401, USA. radixon@noble.org
Abstract:
Significant advances have been made concerning the biosynthesis, regulation and genetic manipulation of plant natural products. These include insights into the structural biology of isoprenoid cyclization and polyketide condensation reactions, a better understanding of the molecular biology of plant cytochrome P450s and O-methyltransferases, and new information on the effects of natural products on human health.
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