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Atypical brachial plexopathy with pseudotumor cerebri.
1Neurology Section, Department of Medicine (1443), King Fahd National Guard Hospital, POB 22490, Riyadh 11426, Saudi Arabia.
European Journal of Neurology
|April 21, 1999
Summary
This case study describes the first instance of brachial plexopathy occurring alongside pseudotumor cerebri syndrome (PTCS). The severe neurological symptoms initially worsened despite treatment but eventually improved, suggesting a potential link between these conditions.
Area of Science:
- Neurology
- Neuroimmunology
Background:
- Pseudotumor cerebri syndrome (PTCS) is a condition characterized by increased intracranial pressure without a clear cause.
- Brachial plexopathy involves damage to the network of nerves in the shoulder and arm.
Observation:
- A 24-year-old woman with a history of PTCS experienced severe neck and shoulder pain, followed by symptoms of bilateral brachial neuritis.
- Concurrently, her PTCS recurred after a prolonged remission.
- The patient developed lumbosacral plexus involvement and vision deterioration, necessitating a lumboperitoneal shunt.
Findings:
- Despite aggressive treatment including methylprednisolone, intravenous immunoglobulins, and cerebrospinal fluid drainage, both brachial plexopathy and PTCS worsened.
- Neurological improvement was observed only after 8 weeks.
- This represents the first reported case of brachial plexopathy associated with PTCS.
Implications:
- The co-occurrence suggests a potential pathological continuum between extended brachial plexopathy and Guillain-Barré syndrome, which has been previously linked to PTCS.
- Further research is needed to elucidate the underlying pathogenesis of this association.
- This case expands the known neurological manifestations associated with PTCS.