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Immediate intraocular pressure response to selective laser trabeculoplasty
P Lanzetta1, U Menchini, G Virgili
1Department of Ophthalmology, University of Udine, Italy.
The British Journal of Ophthalmology
|April 21, 1999
Summary
Selective laser trabeculoplasty effectively lowers intraocular pressure in open-angle glaucoma patients. This glaucoma treatment demonstrated a significant reduction in eye pressure, comparable to standard methods.
Area of Science:
- Ophthalmology
- Glaucoma research
- Laser therapy
Background:
- Selective laser trabeculoplasty (SLT) targets pigmented trabecular meshwork cells.
- SLT aims to preserve trabecular meshwork architecture.
- In vitro studies suggest SLT's efficacy and safety.
Purpose of the Study:
- To evaluate the in vivo intraocular pressure response to SLT.
- To assess the immediate effects of SLT in patients with uncontrolled open-angle glaucoma.
Main Methods:
- Eight eyes with open-angle glaucoma were treated with SLT using a frequency-doubled Q-switched Nd:YAG laser.
- Trabecular meshwork was treated 360 degrees.
- Intraocular pressure was monitored at various intervals post-treatment.
Main Results:
- Preoperative average intraocular pressure was 26.6 mm Hg.
- A significant average IOP reduction of 10.6 mm Hg (39.9%) was observed at 2 hours and 6 weeks post-SLT.
- One eye experienced a transient pressure spike of 10 mm Hg one hour after treatment.
Conclusions:
- Selective laser trabeculoplasty effectively reduces intraocular pressure in open-angle glaucoma.
- The IOP reduction achieved is comparable to standard trabeculoplasty.
- Further research is required to determine the long-term efficacy of SLT.