Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Persistent perineal sinus after proctocolectomy for Crohn's disease.

T Yamamoto1, I M Bain, R N Allan

  • 1University Department of Surgery, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom.

Diseases of the Colon and Rectum
|April 22, 1999
PubMed
Summary

Persistent perineal sinus after proctocolectomy for Crohn's disease is linked to younger age, rectal involvement, and fecal contamination. Surgical treatment for these sinuses is often ineffective, highlighting the need for preventative strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Jejunal Crohn's disease is associated with a higher postoperative recurrence rate than ileocaecal Crohn's disease.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2005
Same author

Assessment of patient pain at colonoscopy: are nurses better than endoscopists?

Journal of the Royal Society of Medicine·2004
Same author

Colonic adenocarcinoma presenting as a cutaneous metastasis in an old operative scar.

Journal of postgraduate medicine·2003
Same author

Life table analysis of hernia following end colostomy construction.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2003
Same author

Bile composition in inflammatory bowel disease: ileal disease and colectomy, but not colitis, induce lithogenic bile.

Alimentary pharmacology & therapeutics·2003
Same author

Wide-lumen stapled anastomosis vs. conventional end-to-end anastomosis in the treatment of Crohn's disease.

Diseases of the colon and rectum·2002

Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Inflammatory Bowel Disease

Background:

  • Persistent perineal sinus is a significant complication following proctocolectomy for Crohn's disease.
  • This condition can lead to considerable patient morbidity.

Purpose of the Study:

  • To identify factors contributing to persistent perineal sinus after proctocolectomy for Crohn's disease.
  • To evaluate the effectiveness of surgical interventions for persistent perineal sinus.

Main Methods:

  • Retrospective review of 145 patients who underwent proctocolectomy for Crohn's disease between 1970 and 1997.
  • Analysis of patient factors and surgical outcomes related to persistent perineal sinus.

Main Results:

Related Experiment Videos

  • Persistent perineal sinus occurred in 23% of patients.
  • Risk factors included younger age, rectal involvement, perianal sepsis, high fistulas, extrasphincteric excision, and fecal contamination.
  • Multivariate analysis identified age, rectal involvement, and fecal contamination as independent predictors.
  • Surgical treatment for persistent sinus was often unsuccessful, with only 9 of 24 patients achieving healing.

    • Conclusions:

    • Extrasphincteric dissection due to extensive disease and fecal contamination during operation increase the likelihood of persistent perineal sinus.
    • Surgical attempts to eradicate persistent perineal sinus have a low success rate.