Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Perineal one-stage pull-through for Hirschsprung's disease.

C T Albanese1, R W Jennings, B Smith

  • 1Department of Surgery, The Fetal Treatment Center, University of California, San Francisco 94143-0570, USA.

Journal of Pediatric Surgery
|April 22, 1999
PubMed
Summary

This study introduces a one-stage transanal repair for Hirschsprung

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Subcutaneous endoscopically assisted ligation (SEAL) of the internal ring for repair of inguinal hernias in children: report of a new technique and early results.

Surgical endoscopy·2007
Same author

The antegrade continence enema procedure: a review of the literature.

Journal of pediatric surgery·1998
Same author

Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases.

European journal of biochemistry·1998
Same author

Lipocortin 1 co-associates with cytokeratins 8 and 18 in A549 cells via the N-terminal domain.

Biochimica et biophysica acta·1998
Same author

Connexin 43 mRNA expression in two experimental models of epilepsy.

Molecular and chemical neuropathology·1998
Same author

Activation of progelatinase B (proMMP-9) by active collagenase-3 (MMP-13).

European journal of biochemistry·1997

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Surgical Innovation

Background:

  • Hirschsprung's disease (HD) is a congenital disorder characterized by the absence of ganglion cells in the distal bowel.
  • Traditional surgical approaches for HD often involve multiple stages and transabdominal dissection.
  • Minimally invasive techniques are being explored to improve outcomes for pediatric surgical conditions.

Purpose of the Study:

  • To present a novel one-stage surgical strategy for Hirschsprung's disease using a transanal approach.
  • To evaluate the feasibility and initial outcomes of this transanal one-stage repair (POOP procedure).

Main Methods:

  • Ten neonates and one toddler with biopsy-proven HD underwent a transanal repair.
  • The procedure involved mucosal dissection starting 0.5 cm proximal to the dentate line, allowing up to 15 cm of bowel resection.

Related Experiment Videos

  • Ganglion cell presence was confirmed intraoperatively via frozen section analysis.

    • Main Results:

    • The mean operative time was 105 minutes, with no intraoperative or postoperative complications.
    • All patients achieved confirmed ganglion cell presence postoperatively.
    • Mean hospital stay was 2 days, with patients averaging 3-6 bowel movements daily without requiring enemas.

    Conclusions:

    • The transanal one-stage operative pull-through (POOP) procedure is a safe and effective adaptation for Hirschsprung's disease.
    • This technique offers a potentially simpler alternative to traditional staged repairs.
    • Long-term follow-up is necessary to fully assess functional outcomes compared to conventional methods.