Related Experiment Video
Updated: Aug 18, 2026
Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Failure of spectro-temporal mapping to detect ventricular late potentials in dogs
C A Calvert1, G J Jacobs, M S Kraus
1Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602, USA.
Objective:
To determine whether ventricular late potentials (LP) identified by time-domain analysis (TDA) of the signal-averaged ECG could be identified by three-dimensional frequency-domain analysis (FDA).
Animals:
11 dogs (9 of which subsequently died suddenly) with ventricular tachyarrhythmias (10 with ventricular tachycardia) and abnormal TDA of the signal-averaged ECG.
Procedure:
Signal-averaged ECG that were abnormal when analyzed in the time domain subsequently were processed further in the frequency domain. Correlation ratios were calculated, and spectro-temporal maps were plotted, which were then compared with control data.
Results:
Three-dimensional FDA did not detect LP.
Conclusions And Clinical Relevance:
LP may be detectable by TDA of the signal-averaged ECG and may be a specific marker for VT and sudden death in some dogs. However, FDA by use of the method applied in this study is invalid.
