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Related Experiment Videos

Quinazoline Yellow SS in cosmetics.

C D Calnan

    Contact Dermatitis
    |June 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Allergic contact dermatitis can occur from Quinazoline Yellow SS (D and C Yellow 11) in cosmetics like lipstick and rouge. This dye can cause significant facial swelling and may necessitate systemic steroid treatment.

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    Area of Science:

    • Dermatology
    • Cosmetic Science
    • Toxicology

    Background:

    • Allergic contact dermatitis (ACD) is an immune response to topical substances.
    • Cosmetics contain various ingredients that can potentially cause skin reactions.
    • Quinazoline Yellow SS (D and C Yellow 11) is a synthetic dye used in cosmetic products.

    Observation:

    • Five cases of ACD were reported in patients using cosmetics containing Quinazoline Yellow SS.
    • Affected products included lipstick and rouge stick.
    • Symptoms included significant edema extending to the eyelids and neck.

    Findings:

    • Four patients exhibited strongly positive patch tests to both the dye and the specific cosmetic product.
    • Two patients required systemic corticosteroid therapy for their severe reactions.

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  • The severity of edema suggests a potent sensitizing capacity of the dye.

    • Implications:

    • Quinazoline Yellow SS (D and C Yellow 11) is a potential allergen in cosmetic formulations.
    • Dermatologists should consider this dye when diagnosing ACD related to makeup.
    • Cosmetic manufacturers should be aware of the allergenic potential of D and C Yellow 11.