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[Posterior mediastinal diffuse pleomorphic lymphoma].

H Nakamura1, F Tsuchica, Y Kariya

  • 1Fifth Department of Internal Medicine, Tokyo Medical College, Ibaraki, Japan.

Nihon Kokyuki Gakkai Zasshi = the Journal of the Japanese Respiratory Society
|April 24, 1999
PubMed
Summary
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A rare case of non-Hodgkin's lymphoma, diffuse pleomorphic type, originated in the posterior mediastinum. This finding is significant as primary mediastinal lymphoma of this type is exceptionally uncommon.

Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Non-Hodgkin's lymphoma (NHL) can present with diverse clinical manifestations.
  • Primary mediastinal lymphomas are uncommon, with specific subtypes rarely reported.

Observation:

  • A 26-year-old male presented with recurrent fever and dysphagia.
  • Radiographic and CT imaging revealed an irregular mass encircling the esophagus in the posterior mediastinum.
  • Open-lung biopsy diagnosed the mass as non-Hodgkin's lymphoma, diffuse pleomorphic type.

Findings:

  • The lymphoma was confined to the posterior mediastinum, with no superficial lymphadenopathy or hepatosplenomegaly.
  • Bone marrow aspiration showed no atypical cells, indicating localized disease.
  • Gallium scintigraphy confirmed focal uptake in the mediastinal region.

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Implications:

  • This case represents a rare instance of primary posterior mediastinal non-Hodgkin's lymphoma.
  • The diffuse pleomorphic type of NHL in this location has not been previously documented.
  • Highlights the importance of considering rare presentations in diagnosing mediastinal masses.