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Related Experiment Videos

Nonaneurysmal thunderclap headache with diffuse, multifocal, segmental, and reversible vasospasm.

D W Dodick1, R D Brown, J W Britton

  • 1Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.

Cephalalgia : an International Journal of Headache
|April 24, 1999
PubMed
Summary
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Recurrent thunderclap headache (TCH) without subarachnoid hemorrhage (SAH) can present with reversible intracranial vasospasm. This suggests a distinct primary TCH profile requiring differentiation from serious conditions.

Area of Science:

  • Neurology
  • Radiology
  • Vascular Neurology

Background:

  • Thunderclap headache (TCH) can indicate serious conditions like subarachnoid hemorrhage (SAH) or venous sinus thrombosis.
  • The pathophysiology and angiographic features of TCH without underlying pathology are not fully understood.

Observation:

  • Two patients presented with recurrent TCH but no SAH.
  • Angiography revealed reversible intracranial vasospasm in both cases.
  • Neither patient had intracranial aneurysms.

Findings:

  • The cases demonstrated reversible intracranial vasospasm as a potential angiographic feature of primary TCH.
  • Both patients experienced a benign clinical outcome.

Implications:

Related Experiment Videos

  • Primary TCH possesses a unique clinical and angiographic profile.
  • It is crucial to distinguish primary TCH from central nervous system vasculitis and SAH.
  • Modified diagnostic criteria may be needed for this syndrome.