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Updated: Aug 12, 2026
Direct Induction of Hemogenic Endothelium and Blood by Overexpression of Transcription Factors in Human Pluripotent Stem Cells
Published on: December 3, 2015
c-kit<low Pluripotent hemopoietic stem cells form CFU-S on day 16
1First Department of Pathology, Kansai Medical University, Moriguchi City, Osaka, Japan.
Abstract:
Using Ly5 congenic mice, we characterized the early differentiation step of pluripotent hemopoietic stem cells. Lineage- (Lin-)/CD71- cells in the bone marrow cells were separated into major histocompatibility complex (MHC) class I(high)/c-kit(low) and MHC class I(high)/c-kit
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