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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Risk factors for strabismus in children born before 32 weeks' gestation

P M Pennefather1, M P Clarke, N P Strong

  • 1Department of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne.

The British Journal of Ophthalmology
|April 27, 1999
PubMed

Insights

Premature infants with cicatricial retinopathy of prematurity, refractive error, family history, or poor neurodevelopment are at higher risk for strabismus. These findings aid in managing premature children and future strabismus etiology research.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Neonatology

Background:

  • Strabismus is a common ocular misalignment.
  • Premature birth is a known risk factor for various developmental issues, including visual impairments.

Purpose of the Study:

  • To identify independent risk factors for strabismus in children born prematurely.
  • To inform management strategies and future research on strabismus etiology.

Main Methods:

  • Prospective study of children born before 32 weeks' gestation.
  • Standardized ophthalmological and pediatric examinations at 2 years of age.
  • Logistic regression analysis to determine risk factors.

Main Results:

  • Strabismus risk increased with cicatricial retinopathy of prematurity, refractive error, family history of strabismus, and poor neurodevelopmental outcome (impaired locomotor skills, hand-eye coordination).
  • Gestational age and regressed acute retinopathy of prematurity were not independent risk factors.
  • 558 premature children were evaluated, representing 98.6% of the study cohort.

Conclusions:

  • Identified independent risk factors for strabismus in premature infants.
  • Distinguished between direct and indirect contributing factors to strabismus.
  • Findings support improved clinical management and targeted research into strabismus causes.
Abstract

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