Related Experiment Videos
Ultrasound biomicroscopic measurement of development of anterior chamber angle
1Department of Ophthalmology, Amagasaki Hospital, Amagasaki, Japan.
Insights
Ultrasound biomicroscopy established normative values for infant anterior eye segments. Key measurements like anterior chamber depth and iris thickness increase with age, aiding pediatric eye development understanding.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Biometry
Background:
- Accurate measurement of the pediatric anterior segment is crucial for understanding ocular development and diagnosing conditions.
- Establishing normative data allows for the identification of deviations from typical growth patterns.
Purpose of the Study:
- To determine age-related normative values for the anterior segment in healthy infants and children.
- To utilize ultrasound biomicroscopy for precise measurements of ocular structures.
Main Methods:
- Ultrasound biomicroscopy was employed to measure anterior segment parameters in 46 infants and children.
- Participants ranged in age from 1 to 60 months.
Main Results:
- Normative values were established for anterior chamber depth, trabecular-iris angle, angle opening distances, and iris thickness.
- All measured parameters demonstrated a significant positive correlation with the logarithm of age.
Conclusions:
- Ultrasound biomicroscopy is an effective tool for precise measurement of the developing pediatric anterior segment.
- Established normative values provide a baseline for assessing ocular development in infants and children.
Aim:
To establish normative values for the anterior segment in normal infants and children in relation to age.
Methods:
Anterior segments were measured in 46 normal infants and children (21 males and 25 females, aged from 1 to 60 months (mean 17.09 (SD 16.99) months)), by use of ultrasound biomicroscopy.
Results:
Anterior chamber depth, trabecular-iris angle, angle opening (trabecular-iris) distances at 250 and 500 microm from the scleral spur, and the thickness of the thickest part of the iris were 1724-3473 microm (2505 (SD 480) microm), 15.35-44.79 degrees (28.74 (7.46) degrees ), 116-367 microm (247.4 (65.9) microm), 166-509 microm (349.5 (87.1) microm), and 249-579 microm (434.6 (74.6) microm), respectively. All factors in this study showed a significant correlation with logarithm of age (r = 0.937, p = 0. 0001; r = 0.867, p = 0.0001; r = 0.929, p = 0.0001; r = 0.917, p = 0. 0001; r = 0.748, p = 0.0001), and significantly correlated with each other.
Conclusions:
Ultrasound biomicroscopy is a powerful tool for obtaining precise images and measurement of the development of the anterior segment in infants and children. Normative values were established for anterior segment dimensions in relation to age. Anterior chamber depth, trabecular-iris angle, angle opening distances at 250 and 500 microm from the scleral spur, and iris thickness showed linear increases in relation to logarithm of age.