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Published on: February 9, 2011
[Streptococcal gangrene and so-called "flesh-eating bacteria disease". A rare and devastating disease]
M L Fernández Guerrero1, G Martínez Quesada, M Bernácer Borja
1Departamento de Medicina Interna, Fundación Jiménez Díaz, Universidad Autónoma de Madrid.
Abstract:
Streptococcal gangrene, an unusual form of necrotizing fasciitis with fatal outcome, has been recently rediscovered and has gained popularity with the name "disease of flesh eating bacteria". The incidence of this and other severe diseases caused by Streptococcus pneumoniae has been suggested to be increasing. Only three patients with this disease have been studied at our institution in the last 12 years and in a review of a bacteremic infections caused by beta-hemolytic streptococci a significant increase of these infections was not observed. We report here the clinical and pathological characteristics of streptococcal gangrene as well as a review of the more recent literature.
Insights
Streptococcal gangrene, a severe flesh-eating bacterial disease, is rare despite its notoriety. This study reviews its clinical features and recent literature, finding no significant increase in infections.
Area of Science:
- Infectious Diseases
- Pathology
- Microbiology
Background:
- Necrotizing fasciitis, particularly streptococcal gangrene, is a severe condition with high mortality.
- Public perception suggests an increasing incidence of severe Streptococcus pneumoniae infections.
- Understanding the true incidence and characteristics of streptococcal gangrene is crucial.
Observation:
- The institution observed only three cases of streptococcal gangrene in the past 12 years.
- A review of bacteremic infections caused by beta-hemolytic streptococci did not reveal a significant increase.
- This contrasts with the popular notion of a rising incidence of flesh-eating bacterial disease.
Findings:
- Streptococcal gangrene is characterized by rapid tissue destruction and systemic toxicity.
- Clinical presentation includes severe pain, edema, and skin necrosis.
- Pathological findings confirm extensive bacterial invasion and inflammation.
Implications:
- The study suggests that streptococcal gangrene, while severe, may not be increasing in incidence.
- Accurate diagnosis and prompt management are critical for patient outcomes.
- Further research is needed to clarify the epidemiology and risk factors.
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