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Measuring costs in multisite randomized controlled trials: lessons from the VA Cooperative Studies Program.

D Hynes1, D Reda, A Giobbie-Hurder

  • 1Department of Veterans Affairs Cooperative Studies Program Coordinating Center, Edward Hines Jr. VA Hospital, Hines, IL 60141-5000, USA. hynes@research.hines.med.va.gov

Medical Care
|April 27, 1999
PubMed
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Measuring health care costs in clinical trials requires robust methods. This study details experiences from the VA Cooperative Studies Program in collecting utilization and economic data for health interventions.

Area of Science:

  • Health Economics
  • Clinical Trial Analysis
  • Health Services Research

Background:

  • Growing interest in the economic impact of novel healthcare interventions.
  • Variability in economic impact assessments due to differing assumptions and methodologies.
  • Need for standardized approaches to measure healthcare costs in clinical studies.

Purpose of the Study:

  • To describe experiences and strategies for measuring healthcare utilization and costs within the VA Cooperative Studies Program.
  • To illustrate methods for economic data collection in multisite randomized clinical trials (RCTs).
  • To inform health planning and policy by providing evidence on the cost of healthcare innovations.

Main Methods:

  • Direct measurement of healthcare utilization within two multisite RCTs.

Related Experiment Videos

  • Collection of economic data concurrently with clinical intervention evaluation.
  • Application of accepted health economic approaches in data collection and analysis.

    • Main Results:

    • Direct measurement of healthcare utilization provides valuable cost data for clinical interventions.
    • Experiences highlight the feasibility of integrating economic assessments into RCTs.
    • Substantial resources are necessary for comprehensive cost-of-care evidence generation.

    Conclusions:

    • Future VA multisite studies should incorporate standardized health economic methodologies.
    • Accurate cost data collection is crucial for effective health planning and policy development.
    • Evidence on the cost of healthcare innovations is vital for both internal and external healthcare systems.