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Renal cell carcinoma with involvement of iris and conjunctiva
G T Ware1, B G Haik, W R Morris
1Department of Ophthalmology, University of Tennessee, Memphis 38163, USA.
Purpose:
To report a case of metastatic renal cell carcinoma with involvement of the iris and bulbar conjunctiva.
Methods:
Case report. A 70-year-old man without known systemic disease developed an iris mass in his left eye. Iridocyclectomy was performed to remove the iris mass.
Results:
Histopathologically, the iris mass was consistent with metastatic renal cell carcinoma. Further evaluation disclosed a mass of the left kidney. The patient underwent a left nephrectomy and was found to have renal cell carcinoma, with focal penetration into the renal capsule. One month after the nephrectomy, he developed a highly vascular nodule of the left bulbar conjunctiva. An excisional biopsy was performed, and histopathology disclosed an additional focus of renal cell carcinoma.
Conclusions:
Iris and conjunctival involvement may be a clinical manifestation of renal cell carcinoma. Renal cell carcinoma should be considered in the differential diagnosis of a fleshy, vascular iris and a conjunctival nodule.