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Allogeneic bone marrow transplantation for advanced Waldenstrom's macroglobulinemia

R Martino1, A Shah, P Romero

  • 1Clinical Hematology Division, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

Bone Marrow Transplantation
|April 28, 1999
PubMed

Waldenstrom's disease is a lymphoproliferative disorder that is typically treated with plasmapheresis and/or alkylating agents. In young patients, other lymphoproliferative disorders have been treated with allogeneic transplantation. Two patients with aggressive Waldenstrom's disease, who progressed in spite of multi-agent chemotherapy and autologous stem cell transplantation, in one case, underwent allogeneic transplantation from their HLA-identical donors. Both remain alive with event-free survivals of more than 3, and more than 9 years, respectively. Allogeneic transplantation should be considered for young patients with Waldenstrom's disease.

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