Related Experiment Videos
Tissue response to an epoxy resin-based root canal sealer
M R Leonardo1, L A da Silva, W A Almeida
1Department of Endodontics, School of Dentistry, Araraquara, Paulista State University, Brazil.
Endodontics & Dental Traumatology
|April 29, 1999
Summary
AH Plus, an epoxy resin-based root canal sealer, showed no inflammation or necrosis and promoted hard tissue formation. Fill Canal, a zinc oxide-eugenol based sealer, induced moderate periapical inflammation.
Area of Science:
- Endodontics
- Biomaterials Science
- Dental Histology
Background:
- Root canal sealers are crucial for endodontic treatment success.
- Evaluating sealer biocompatibility and tissue response is essential for clinical application.
Purpose of the Study:
- To compare the periapical tissue response to AH Plus (epoxy resin-based) and Fill Canal (zinc oxide-eugenol based) root canal sealers.
Main Methods:
- Histological evaluation of 34 instrumented dog premolar root canals filled with gutta-percha and either AH Plus or Fill Canal.
- Staining with hematoxylin-eosin or Mallory's trichrome.
Main Results:
- AH Plus demonstrated no associated inflammatory cells or necrosis, with hard tissue formation observed in 14 specimens.
- Fill Canal elicited a moderate inflammatory response in the periapical region, primarily adjacent to the sealer.
Conclusions:
- AH Plus exhibits favorable biocompatibility and promotes hard tissue apposition.
- Fill Canal demonstrates a moderate inflammatory potential in periapical tissues.