Related Experiment Video
Updated: Oct 23, 2026

Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons
Published on: June 6, 2025
Characterization of an alphoid subfamily located near p-arm sequences on human chromosome 22
I Eisenbarth1, D König-Greger, G Wöhr
1Abteilung Humangenetik, Universität Ulm, Albert-Einstein-Allee 11, Germany.
Abstract:
The centromeric heterochromatin of all human chromosomes is composed of tandemly repeated alpha satellite DNA. Here we describe another alphoid subfamily that maps to human chromosome 22 as determined by FISH. The alphoid sequences were isolated from three YAC-clones carrying DNA from the pericentromeric region of the short arm of human chromosome 22 and limited amounts of alphoid DNA. This property enabled us to map the members of the subfamily to the border of the centromeric region and the short arm of the chromosome. The new alphoid subfamily may contribute to the closure of the gap remaining between the centromeric and short-arm maps of human chromosome 22.
Related Concept Videos
Karyotyping
Polytene Chromosomes
Polytene Chromosomes
Protein Families
Nucleoid
Heterochromatin
Constitutive heterochromatin: It is a highly compact region of chromatin that is mostly concentrated in the centromere and telomere. Unlike euchromatin, the amino acid at 9th...

