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Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
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Management of pre-eclampsia and haemolysis, elevated liver enzymes, and low platelets syndrome

D O Anumba1, S C Robson

  • 1Department of Obstetrics and Gynaecology, The Royal Victoria Infirmary, Newcastle upon Tyne, UK.

Current Opinion in Obstetrics & Gynecology
|April 29, 1999
PubMed

Insights

Pre-eclampsia is a significant cause of maternal and fetal health problems, linked to placental issues and endothelial dysfunction. This review covers recent advances in its diagnosis, treatment, prediction, prevention, and management of HELLP syndrome.

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Cardiovascular Research

Background:

  • Pre-eclampsia poses a major threat to maternal and fetal well-being.
  • Clinical manifestations are associated with impaired placentation and endothelial dysfunction.
  • Understanding these underlying mechanisms is crucial for effective management.

Purpose of the Study:

  • To review recent advancements in pre-eclampsia research.
  • To discuss contemporary issues in diagnosing, treating, predicting, and preventing pre-eclampsia.
  • To address the management of haemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome.

Main Methods:

  • Literature review of recent publications.
  • Synthesis of current knowledge on pre-eclampsia.
  • Discussion of clinical management strategies.

Main Results:

  • Recent publications offer new insights into diagnosis and treatment.
  • Advances in prediction and prevention strategies are emerging.
  • Current management of HELLP syndrome involves addressing its complex features.

Conclusions:

  • Continued research is vital for improving pre-eclampsia outcomes.
  • Integrated approaches to diagnosis, treatment, and prevention are necessary.
  • Effective management of HELLP syndrome requires a multidisciplinary approach.

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