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Serum cholesterol and impulsivity in personality disorders
A S New1, E M Sevin, V Mitropoulou
1Department of Psychiatry, Mount Sinai School of Medicine and Bronx VA Medical Center, New York NY, USA.
Psychiatry Research
|April 29, 1999
Summary
This study found that individuals with borderline personality disorder have lower serum cholesterol levels. This suggests a potential link between this personality disorder and reduced cholesterol, particularly in males.
Area of Science:
- Neuropsychology
- Psychiatry
- Biochemistry
Background:
- Serum cholesterol levels have been previously linked to impulsive and aggressive behaviors.
- Understanding biochemical correlates of personality disorders is crucial for advancing psychiatric research.
Purpose of the Study:
- To investigate the association between serum cholesterol levels and impulsive aggression measures.
- To explore this relationship specifically within a cohort of patients diagnosed with personality disorders.
Main Methods:
- Forty-two patients with personality disorders were recruited.
- Fasting serum cholesterol was quantified using standard enzymatic assays.
- Analysis of variance (ANOVA) was employed to examine gender and diagnosis interactions with cholesterol levels.
Main Results:
- Patients diagnosed with borderline personality disorder exhibited significantly lower serum cholesterol compared to those with other personality disorders.
- A significant interaction between gender and diagnosis was observed, with male patients displaying lower cholesterol levels.
- These findings indicate a potential correlation between borderline personality disorder and diminished serum cholesterol.
Conclusions:
- Borderline personality disorder may be associated with lower serum cholesterol levels.
- The interplay between gender and diagnosis warrants further investigation regarding cholesterol levels in personality disorders.