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Perinatal outcome after in-vitro fertilization-surrogacy
1Huntington Reproductive Center, Pasadena, California, USA.
Human Reproduction (Oxford, England)
|April 30, 1999
Summary
In vitro fertilization (IVF)-surrogacy offers reassuring perinatal outcomes. While multiple gestations increase risks like prematurity, IVF-surrogates experience fewer hypertensive disorders and bleeding events.
Area of Science:
- Reproductive Medicine
- Perinatology
- Obstetrics
Background:
- In vitro fertilization (IVF) is a key technology for infertility treatment.
- IVF-surrogacy involves a surrogate carrying a pregnancy for intended parents.
- Limited data exists on the perinatal outcomes of IVF-surrogacy pregnancies.
Purpose of the Study:
- To evaluate and compare the perinatal outcomes of IVF-surrogacy pregnancies with standard IVF pregnancies.
- To assess prenatal and delivery care for IVF-surrogacy cases.
Main Methods:
- Retrospective analysis of medical records from multiple hospitals.
- Telephone interviews with physicians, IVF-surrogates, and commissioning mothers.
- Comparison of outcomes between singleton, twin, and triplet gestations in IVF-surrogacy.
Main Results:
- IVF-surrogates carrying multiples delivered earlier; newborns were lighter with higher rates of low birth weight and prematurity.
- Pregnancy-induced hypertension and third-trimester bleeding were significantly lower in IVF-surrogates.
- Cesarean section rates were higher for multiple gestations carried by IVF-surrogates.
Conclusions:
- IVF-surrogacy generally provides reassuring perinatal outcomes.
- While risks associated with multiple gestations exist, IVF-surrogates show improved maternal safety profiles for certain complications.
- The study supports IVF-surrogacy as a viable option for couples seeking to build their families.