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Related Experiment Videos

[Multifocal invasive Kingella kingae infection].

H Sarda1, D Ghazali, M Thibault

  • 1Service de pédiatrie, hôpital Victor-Dupouy, Argenteuil, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|May 1, 1999
PubMed
Summary
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Kingella kingae, a bacterium causing severe infections like septicemia, meningitis, and endocarditis in children, can be successfully treated with adjusted antibiotic therapy. This case highlights favorable outcomes with appropriate antimicrobial treatment strategies.

Area of Science:

  • Pediatric Infectious Diseases
  • Clinical Microbiology
  • Bacteriology

Background:

  • Kingella kingae is an increasingly recognized cause of invasive infections in young children.
  • This bacterium typically requires specific culture media for isolation and identification.
  • Osteoarticular and cardiac infections are common manifestations of Kingella kingae.

Observation:

  • A 2-year-old, non-immunodeficient child presented with severe septicemia caused by Kingella kingae.
  • The infection progressed to meningitis, arthritis of the knee, and endocarditis.
  • The patient received a prolonged course of adjusted antibiotic therapy.

Findings:

  • Successful treatment of Kingella kingae endocarditis involved a combination of ceftriaxone and amikacin, followed by oral amoxicillin.

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  • The overall outcome for the child was favorable despite the severe and disseminated nature of the infection.
  • Kingella kingae demonstrates tropism for osteoarticular and cardiac systems.

    • Implications:

    • This case underscores the importance of considering Kingella kingae in the differential diagnosis of invasive pediatric infections.
    • Prompt and appropriate antibiotic selection is crucial for favorable outcomes in invasive Kingella kingae infections.
    • Understanding the bacteriologic characteristics and antibiotic susceptibility of Kingella kingae aids in effective clinical management.