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Related Experiment Videos

[Multifocal invasive Kingella kingae infection].

H Sarda1, D Ghazali, M Thibault

  • 1Service de pédiatrie, hôpital Victor-Dupouy, Argenteuil, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|May 1, 1999
PubMed
Summary

Kingella kingae, a bacterium causing severe infections like septicemia, meningitis, and endocarditis in children, can be successfully treated with adjusted antibiotic therapy. This case highlights favorable outcomes with appropriate antimicrobial treatment strategies.

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Area of Science:

  • Pediatric Infectious Diseases
  • Clinical Microbiology
  • Bacteriology

Background:

  • Kingella kingae is an increasingly recognized cause of invasive infections in young children.
  • This bacterium typically requires specific culture media for isolation and identification.
  • Osteoarticular and cardiac infections are common manifestations of Kingella kingae.

Observation:

  • A 2-year-old, non-immunodeficient child presented with severe septicemia caused by Kingella kingae.
  • The infection progressed to meningitis, arthritis of the knee, and endocarditis.
  • The patient received a prolonged course of adjusted antibiotic therapy.

Findings:

  • Successful treatment of Kingella kingae endocarditis involved a combination of ceftriaxone and amikacin, followed by oral amoxicillin.

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  • The overall outcome for the child was favorable despite the severe and disseminated nature of the infection.
  • Kingella kingae demonstrates tropism for osteoarticular and cardiac systems.

    • Implications:

    • This case underscores the importance of considering Kingella kingae in the differential diagnosis of invasive pediatric infections.
    • Prompt and appropriate antibiotic selection is crucial for favorable outcomes in invasive Kingella kingae infections.
    • Understanding the bacteriologic characteristics and antibiotic susceptibility of Kingella kingae aids in effective clinical management.