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Risperidone and clozapine combination for the treatment of refractory schizophrenia
A L Morera1, P Barreiro, J L Cano-Muñoz
1Department of Internal Medicine and Psychiatry, Faculty of Medicine, University of La Laguna, Tenerife, Spain.
Acta Psychiatrica Scandinavica
|May 1, 1999
Abstract:
Clozapine is the most widely used antipsychotic drug for the treatment of refractory schizophrenia. Here we report the case of two residual schizophrenic patients refractory to conventional antipsychotics who showed a poor response to atypical antipsychotics. The combination of risperidone and clozapine produced a noticeable improvement in the patients' clinical status and a shortening of the treatment response latency.