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Updated: Aug 1, 2026
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
Color Doppler image of central retinal artery of eyes with an intraconal mass
1Department of Ophthalmology, Ramón y Cajal Hospital, Alcalá de Henares University, Madrid, Spain. vcuarteror@nexo.es
Purpose:
Retinal ischemia secondary to hypoperfusion of the central retinal artery is recognized as one factor that may contribute to the development of loss of vision in eyes with intraorbital tumors. We study intraorbital tumors which produce motility disturbances and visual problems by color Doppler imaging to evaluate this factor.
Methods:
We examined the central retinal artery velocities of 3 patients with disc edema caused by intraconal masses (2 cavernous hemangiomas and 1 presumed optic nerve glioma) via color Doppler imaging.
Results:
The time-velocity waveform demonstrated abnormally high vascular resistance in the central retinal artery of all affected eyes in the primary position compared with the normal waveform seen in the other eyes. We compared the pulsatility index of eyes with an intraconal mass and contralateral, control eyes using Student's t test for paired samples and significant differences were noted between both groups (p< 0.01).
Conclusions:
Intraconal tumors could produce increased pressure in the optic nerve sheath and the optic nerve tissue which could be associated with impaired retinal and optic nerve blood flow and the subsequent amaurosis encountered with intraorbital tumors.
