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Correlation between in vitro susceptibility determined by E test and response to therapy with amphotericin B: results
1Department of Medicine, Division of Infectious Diseases, University of Florida College of Medicine, VA Medical Center, Gainesville, Florida, USA.
Antimicrobial Agents and Chemotherapy
|May 1, 1999
Abstract:
Ninety-nine Candida bloodstream isolates underwent testing for susceptibility to amphotericin B by the E test, and the results were correlated with patients' responses to amphotericin B. The MICs for isolates that were associated with therapeutic failure were significantly higher than the MICs for those associated with therapeutic success. A MIC of >/=0.38 microgram/ml identified isolates likely to be associated with therapeutic failure.