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Epileptogenic mineralization: pathological variants with good prognosis
Annals of Neurology
|October 1, 1977
Summary
Mineralized brain lesions, including hamartomas and choristomas, can cause seizures. Surgical intervention for these "brain stones" often leads to seizure relief.
Area of Science:
- Neurology
- Neurosurgery
- Radiology
Background:
- Intracranial calcifications can present as diverse pathologies.
- Seizures are a common neurological symptom associated with focal brain lesions.
Observation:
- Four cases of symptomatic, grossly mineralized brain lesions were analyzed.
- Lesions included two hamartomas, one choristoma, and an idiopathic calcification ('brain stone').
- These pathologies were identified using standard roentgenograms.
Findings:
- Mineralized brain lesions, despite their varied origins, can be detected via conventional radiography.
- Surgical resection of these lesions resulted in significant amelioration of seizure activity in all described cases.
Implications:
- Routine roentgenograms are valuable for diagnosing mineralized brain lesions causing seizures.
- Surgical treatment offers a viable therapeutic option for seizure control in affected patients.