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Updated: Aug 16, 2026

Preparation of Rat Serum Suitable for Mammalian Whole Embryo Culture
Published on: August 3, 2014
[Micrometric and morphological assessment of early stage rat embryos -- application for in vivo teratology testing]
B Biernacki1, B Włodarczyk, M Minta
1Zakładu Farmakologii i Toksykologii Państwowego Instytutu Weterynaryjnego w Puławach.
Abstract:
Authors presented the whole embryo culture (WEC) method suggested for embryotoxicity study. The present paper concentrates on morphological scoring system proposed by Brown and Fabro in 1981. The scoring system provides a precise index of embryonic development and allows a quantitative comparison of development and growth. In our study we used this system with slight modification for assessing an 86 control rat embryos. We have found that routine use of this scoring system in teratology embryo culture experiments may afford further benefits.

