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Updated: Aug 10, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
[A morphological assessment of periodontal tissue status in the postshock traumatic period in an experiment]
Abstract:
Shockogenic sublethal mechanical multiple injuries were induced in outbred albino rats according to the method developed by Noble-Collip and periodontal tissues were examined histomorphologically in various periods after shock. Atrophic changes in periodontal tissues and dental pulp progressed starting from day 1 and reached the maximum on day 28. The greatest shifts were observed in the gingivodental epithelium (hyperkeratosis), periodontium (lymphocyte and macrophage infiltration), alveolar bone (lacunar resorption), and pulp (odontoblast reduction and decreased pulpocyte count). Phasic reactive changes in the periodontium after shock and trauma require timely correction.

