Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bilirubin adsorbent column for plasma perfusion.

Y Takenaka1

  • 1Technical Department, Asahi Medical Co., Ltd., Tokyo, Japan.

Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis
|May 4, 1999
PubMed
Summary

Plasma exchange removes toxins but risks infection. A new bilirubin adsorption column offers a safer alternative for treating liver failure by removing toxic substances from blood.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes in the composition of molecular species of covalently bound and free ceramides [EOS], and their correlation with disease severity in atopic dermatitis.

Experimental dermatology·2024
Same author

Ischaemic skin ulcers with neurofibromatosis 1 successfully treated with stent implantation.

Clinical and experimental dermatology·2021
Same author

Light-induced displacement of a microbead through the thermal expansion of liquid crystals.

Soft matter·2016
Same author

Royal Jelly from Apis cerana japonica and Apis mellifera.

Bioscience, biotechnology, and biochemistry·2016
Same author

Dewetting of a droplet induced by the adsorption of surfactants on a glass substrate.

Soft matter·2014
Same author

CD10 as a novel marker of therapeutic resistance and cancer stem cells in head and neck squamous cell carcinoma.

British journal of cancer·2014

Area of Science:

  • Hepatology
  • Biomedical Engineering
  • Toxicology

Background:

  • Plasma exchange is used to remove protein-bound toxins in hepatic failure.
  • It requires human plasma, posing risks of infection and requiring coagulation factor replacement.
  • Bilirubin is a key toxin removed, and alternative methods are sought.

Purpose of the Study:

  • To review the characteristics of a novel bilirubin adsorbent column.
  • To evaluate its potential as a safer alternative to plasma exchange for toxin removal.

Main Methods:

  • Review of existing literature on plasma exchange and bilirubin adsorption.
  • Description of the technical characteristics of the bilirubin adsorption column.
  • Discussion of its application in plasma perfusion.

Main Results:

  • The bilirubin adsorption column effectively removes bilirubin from blood or plasma.
  • This method avoids the need for human plasma, mitigating infection risks.
  • The adsorbent has been practically applied in Japan.

Conclusions:

  • The bilirubin adsorption column is a promising alternative to plasma exchange for managing hepatic failure.
  • It offers a safer approach to eliminating protein-bound toxins like bilirubin.
  • Further research may validate its widespread clinical use.

Related Experiment Videos