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Red cell apheresis: new concepts of blood component processing
Summary
Automated red cell apheresis procedures yield high-quality blood components meeting European standards. These efficient methods offer comparable or superior storage results to manual collection, enhancing blood supply self-sufficiency.
Area of Science:
- Transfusion Medicine
- Hematology
Background:
- Red cell apheresis procedures have been implemented in Europe, with over 6,000 automated collections processed.
- Evaluation of different apheresis protocols (RBCPS, RBCP, SDP-RBC) is crucial for optimizing blood component collection.
Purpose of the Study:
- To assess the quality and storage characteristics of blood components obtained through various automated red cell apheresis protocols.
- To compare the efficacy of apheresis methods with traditional manual collection techniques.
Main Methods:
- Analysis of automated blood component collections using RBCPS, RBCP, and SDP-RBC protocols.
- Quality assessment of red cell concentrates (42-day storage) and platelet concentrates (5-day storage).
- Measurement of processing times for each apheresis protocol.
Main Results:
- All collected blood components met European guidelines.
- Red cell concentrate storage quality was equivalent or superior to manual collection (e.g., 2,3-DPG, rheological parameters).
- Platelet concentrate storage data were comparable to standard platelet apheresis; all products remained sterile.
Conclusions:
- Automated red cell apheresis is an effective method for collecting high-quality blood components.
- Apheresis procedures present opportunities for revising national blood and plasma programs to improve self-sufficiency.
- The efficiency and quality of apheresis support its role in modern transfusion medicine.