Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention

An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells.

Oncogene·2013

TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118.

Oncogene·2006

Quantification of tissue inhibitor of metalloproteinases 2 in plasma from healthy donors and cancer patients.

Scandinavian journal of immunology·2005

Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells.

Journal of the National Cancer Institute·2001

Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.

Cancer research·2001

The role of matrix metalloproteinases in tumor invasion, metastasis, and angiogenesis.

Surgical oncology clinics of North America·2001

Immune Cell-Specific SMN Expression and Sustained Immune Alterations in Treated Spinal Muscular Atrophy.

The Journal of clinical investigation·2026

Excessive EFHD1-dependent ER-mitochondrial contacts drive a maladaptive antiviral response in metabolic liver disease.

The Journal of clinical investigation·2026

B-cell depletion improves therapeutic index of combination checkpoint blockade in patients with advanced melanoma.

The Journal of clinical investigation·2026

RhoA wild-type allele loss unleashes the cancer driver function of RhoA E40Q.

The Journal of clinical investigation·2026

FBXW5 blunts RIGI/MDA5-IFN signaling to drive immunoevasion and chemo-immune resistance in triple-negative breast cancer models.

The Journal of clinical investigation·2026

Convection-enhanced delivery of dexamethasone in glioma models suppresses myeloid inflammation while avoiding systemic toxicities.

The Journal of clinical investigation·2026

A suite of eight Toxoplasma gondii effectors cooperates to activate the non-canonical NF-κB pathway.

mBio·2026

Laminin - myCAF interplay promotes α6-integrin-mediated breast cancer cell invasion.

Lab on a chip·2026

[Efficacy and safety of injectable sodium hyaluronate gel in correcting moderate to severe nasolabial folds: a single-center, randomized, double-blind, controlled trial].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences·2026

TNS1/TAGLN-enriched endometrial stromal cells is associated with a persistent fibrotic microenvironment in intrauterine adhesion.

Frontiers in cell and developmental biology·2026

Sulf1 regulates inflammation via modulation of TGF-β dependent epicardial activation.

EMBO reports·2026

SNHG26 orchestrates pro-fibrotic fibroblast maintenance via PTBP1-mediated alternative polyadenylation of AKT3 in dermal fibrosis.

Proceedings of the National Academy of Sciences of the United States of America·2026

Related Experiment Videos

Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention

Related Concept Videos

An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells.

TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118.

Quantification of tissue inhibitor of metalloproteinases 2 in plasma from healthy donors and cancer patients.

Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells.

Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.

The role of matrix metalloproteinases in tumor invasion, metastasis, and angiogenesis.

Immune Cell-Specific SMN Expression and Sustained Immune Alterations in Treated Spinal Muscular Atrophy.

Excessive EFHD1-dependent ER-mitochondrial contacts drive a maladaptive antiviral response in metabolic liver disease.

B-cell depletion improves therapeutic index of combination checkpoint blockade in patients with advanced melanoma.

RhoA wild-type allele loss unleashes the cancer driver function of RhoA E40Q.

FBXW5 blunts RIGI/MDA5-IFN signaling to drive immunoevasion and chemo-immune resistance in triple-negative breast cancer models.

Convection-enhanced delivery of dexamethasone in glioma models suppresses myeloid inflammation while avoiding systemic toxicities.

A suite of eight Toxoplasma gondii effectors cooperates to activate the non-canonical NF-κB pathway.

Laminin - myCAF interplay promotes α6-integrin-mediated breast cancer cell invasion.

[Efficacy and safety of injectable sodium hyaluronate gel in correcting moderate to severe nasolabial folds: a single-center, randomized, double-blind, controlled trial].

TNS1/TAGLN-enriched endometrial stromal cells is associated with a persistent fibrotic microenvironment in intrauterine adhesion.

Sulf1 regulates inflammation via modulation of TGF-β dependent epicardial activation.

SNHG26 orchestrates pro-fibrotic fibroblast maintenance via PTBP1-mediated alternative polyadenylation of AKT3 in dermal fibrosis.

Related Experiment Videos

Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention

Related Concept Videos

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