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Case of gonadoblastoma in a 9-year-old boy without physical abnormalities
T Hatano1, Y Yoshino, Y Kawashima
1Department of Urology, Jikei University School of Medicine, Tokyo, Japan.
Background:
A 9-year-old boy was admitted to Jikei University Hospital complaining of gradual enlarging of the left scrotal contents.
Methods/Results:
Physical examination was significant for bilateral descended testicles. No abnormalities were detected in the testicles or along the spermatic cords. Scrotal ultrasound showed that hyperechoic shadows were recognized in the central area of the left testicle. Subsequent testicular biopsy and histopathological examination showed intratubular malignant germ cells in the testicular tubules. One week later, left orchiectomy was performed.
Conclusions:
Histopathological evaluation revealed gonadoblastoma. Gonadoblastoma, a rare gonadal neoplasm, is composed of germ cells and sex cord derivatives and usually occurs in phenotypically female patients with gonadal dysgenesis. To date, only three cases of gonadoblastoma have been reported in anatomically normal male patients with scrotal testicles. We report on a case of gonadoblastoma unaccompanied by a germ cell tumor in a physically normal male.