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Prominent effect of immunoadsorption plasmapheresis therapy in a patient with chronic inflammatory demyelinating
A Inoue1, K Oguchi, T Iwahashi
1Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Abstract:
We encountered a patient with chronic inflammatory demyelinating polyneuropathy associated with hepatitis B infection. Immunohistochemical study revealed the deposition of immune complex composed of hepatitis B surface antigen (HBsAg) both around the endoneural capillary and in the endoneurium. Neurological signs were significantly improved by immunoadsorption plasmapheresis (IAPP) treatment without incorporating corticosteroid hormone therapy; weekly long-term IAPP has successfully maintained the patient's condition.
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