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In vitro effectiveness study of three hydrodynamic thrombectomy devices
S Müller-Hülsbeck1, C Bangard, H Schwarzenberg
1Department of Radiology, University Hospital, Kiel, Germany.
Radiology
|May 6, 1999
Summary
Three hydrodynamic thrombectomy devices demonstrated varying in vitro efficacies. The Shredding Embolectomy Thrombectomy catheter and Hydrolyser may increase anemia risk, but hydrodynamic thrombectomy can reduce thrombolytic therapy needs.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Biomedical Engineering
Background:
- Hydrodynamic thrombectomy utilizes fluid dynamics to remove blood clots.
- Comparing the efficacy of different thrombectomy devices is crucial for clinical decision-making.
Purpose of the Study:
- To evaluate and compare the in vitro performance of three hydrodynamic thrombectomy devices: Angiojet (AJ), Hydrolyser (HL), and Shredding Embolectomy Thrombectomy (SET) catheter.
Main Methods:
- A flow model was used to simulate clot removal with AJ, HL, and SET catheters.
- Thrombectomy time, fluid dynamics (isovolumetric performance), and mean embolus weight were measured for each device.
Main Results:
- Thrombectomy times varied significantly, with HL being the fastest (10.22s) and AJ with a guidewire the slowest (37.73s).
- The SET catheter and HL showed potential for increased procedure-related anemia.
- Device performance, including embolus retrieval, differed substantially across the tested thrombectomy systems.
Conclusions:
- Significant performance differences exist among hydrodynamic thrombectomy devices.
- The SET catheter and HL may pose a higher risk for procedure-related anemia.
- Hydrodynamic thrombectomy shows promise in reducing the reliance on thrombolytic agents in clinical practice.