Possible development of idiopathic sclerosing encapsulating peritonitis

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Updated: Oct 3, 2026

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

H Yanagi1, M Kusunoki, T Yamamura

  • 1Second Department of Surgery, Hyogo College of Medicine, Japan.

Hepato-Gastroenterology
|May 6, 1999
PubMed

Insights

This case study details a rare instance of idiopathic sclerosing encapsulating peritonitis (SEP), a condition causing bowel obstruction. Early intervention and motility regulators improved patient outcomes, offering insights into SEP development.

Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Sclerosing encapsulating peritonitis (SEP) is a rare condition characterized by a fibrous membrane encasing the small bowel.
  • Idiopathic SEP presents diagnostic and therapeutic challenges, often requiring surgical intervention.

Observation:

  • A patient undergoing distal gastrectomy for gastric cancer developed unusual membranous encapsulation of small bowel loops post-operatively.
  • A subsequent laparotomy revealed typical SEP with a thick, fibrotic membrane causing complete small bowel encasement and prolonged transit issues.

Findings:

  • Surgical lysis of adhesions and membrane stripping, along with Braun's anastomosis, were performed.
  • Post-operatively, the patient experienced persistent epigastric fullness and diarrhea.
  • Administration of trimebutine maleate significantly improved symptoms, suggesting a role for motility regulation.

Implications:

  • This case may illustrate a potential developmental pathway for idiopathic SEP.
  • Motility regulators could be beneficial in managing symptoms associated with abnormal intestinal motility in SEP patients.

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