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Updated: Oct 23, 2026
Right Hemihepatectomy by Suprahilar Intrahepatic Transection of the Right Hemipedicle using a Vascular Stapler
Published on: January 25, 2010
Liver regeneration after extended right hemihepatectomy in patients with hilar or diffuse bile duct carcinoma
S Miyagawa1, S Kawasaki, T Noike
1First Department of Surgery, Shinshu University, School of Medicine, Matsumoto, Japan.
Background/Aims:
The degree to which liver size can be restored and the factors that determine liver regeneration after major hepatectomy are not well understood.
Methodology:
Liver volumes (LV) were estimated from computed tomography scans in 16 patients who survived with no evidence of cancer recurrence more than 1 year after extended right hemihepatectomy.
Results:
The mean percentage of LV at 1 year was 75.7 +/- 9.5% and LV did not change significantly beyond 1 year after surgery. A significant correlation was observed between LV at 1 year and body surface area (r = 0.79, p < 0.001). A significant inverse correlation was observed between LV at 1 year and the plasma retention rate of indocyanine green at 15 min (the ICG 15 value) (r = -0.72, p < 0.01).
Conclusions:
In adults, the liver does not always regain its pre-operative size after hepatectomy. Patients' body size and intrinsic liver function or liver blood flow, represented by the ICG 15 value, may be related to regenerated liver size.
