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Related Experiment Videos

Post-traumatic endophthalmitis: causative organisms and visual outcome.

A M Abu el-Asrar1, S A al-Amro, A A al-Mosallam

  • 1Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

European Journal of Ophthalmology
|May 7, 1999
PubMed
Summary

This study identified causative organisms in post-traumatic endophthalmitis, finding Clostridium perfringens was frequent. Prompt treatment with vitrectomy and antibiotics is crucial for preserving vision after penetrating eye trauma.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Trauma Surgery

Background:

  • Post-traumatic endophthalmitis is a severe intraocular infection following penetrating eye injuries.
  • Early identification of causative pathogens and visual outcomes is critical for effective management.

Observation:

  • A review of 18 culture-positive cases of endophthalmitis after penetrating ocular trauma was conducted.
  • The most frequent organisms identified were Staphylococcus epidermidis and gram-negative bacteria, with a notable isolation rate of Clostridium perfringens.
  • Bacillus species were not found to be a cause in this series.

Findings:

  • Fifty percent of cases involved intraocular foreign bodies.
  • Final visual acuity better than 20/400 was achieved in 44% of patients.

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  • Despite treatment, 27.7% had counting fingers vision, 11% had no light perception, and 16.6% required eye removal.

    • Implications:

    • The spectrum of organisms causing post-traumatic endophthalmitis may vary geographically, with a high incidence of Clostridium perfringens noted.
    • Prompt surgical intervention (vitrectomy) and antibiotic therapy (intravitreal) are essential for improving visual outcomes in these devastating infections.