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Related Experiment Videos

Myxoid dermatofibroma.

B G Zelger1, E Calonje, B Zelger

  • 1Department of Pathology, University of Innsbruck, Austria.

Histopathology
|May 7, 1999
PubMed
Summary
This summary is machine-generated.

This study details a rare myxoid dermatofibroma variant with significant mucin. These fibrohistiocytic lesions can be mistaken for cutaneous myxomas, highlighting the need for careful histopathological evaluation.

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Area of Science:

  • Dermatopathology
  • Histopathology
  • Oncology

Background:

  • Dermatofibromas are common skin tumors.
  • A rare variant with myxoid changes presents diagnostic challenges.

Purpose of the Study:

  • To describe the clinicopathological features of seven cases of myxoid dermatofibroma.
  • To differentiate this variant from other myxoid skin lesions.

Main Methods:

  • Retrospective clinicopathological analysis of seven cases.
  • Histopathological examination including immunohistochemistry.
  • Electron microscopy was performed in one case.

Main Results:

  • Lesions occurred on lower extremities of young to middle-aged females.

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  • Histology showed abundant stromal mucin and spindle cells.
  • Immunohistochemistry confirmed fibrohistiocytic origin (KiM1p positive).

    • Conclusions:

    • Myxoid dermatofibroma is a rare fibrohistiocytic variant.
    • It can be misdiagnosed as cutaneous myxoma.
    • Accurate histopathological diagnosis is crucial.