Related Experiment Video
Updated: Jul 24, 2026

Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery
Published on: October 20, 2023
Failure to improve outcome in acute mesenteric ischaemia: seven-year review
N Mamode1, I Pickford, P Leiberman
1Peripheral Vascular Unit, Glasgow Royal Infirmary, Scotland. nizam@mamode.demon.co.uk
Objective:
To determine whether the prognosis of acute mesenteric ischaemia has changed over the past seven years.
Design:
Retrospective study.
Setting:
Teaching hospital, Scotland.
Subjects:
57 patients who presented to this hospital between January 1987 and December 1993 with acute mesenteric ischaemia.
Main Outcome Measures:
Morbidity, mortality and prognostic features.
Results:
46 of the 57 patients died. Only 18(32%) patients were accurately diagnosed before operation or death. Clinical presentation, white cell count, and serum amylase activity were not helpful in the diagnosis. Only 3 patients had mesenteric angiography, and none were given lytic agents or vasodilators.
Conclusion:
Mortality from acute mesenteric ischaemia has not changed during the past two decades and in the absence of an accurate diagnostic test is unlikely to do so.

